Abstract Library
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Participants of the ENETS Conference in 2024 can now access the abstract booklet, e-posters and videos, slide decks of talks, the poster carousel, and more via My ENETS.
ENETS Abstract Search
Introduction: Vascular adhesion protein-1 (VAP-1) is a novel driver of tissue inflammation and fibrosis.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Shah T, Sagar V, Neil D, Liu B, Barriuso J,
Keywords: carcinoid, GEP-NET, VAP-1, ECM, tumour stroma, biomarker,
Introduction: Extracellular fragments derived from membrane receptors can play relevant functional roles in certain tumoral pathologies and could provide novel diagnostic or therapeutic tools. We have identified a novel truncated somatostatin receptor type 5 variant, sst5TMD4, which is overexpressed and functionally active in different endocrine-related cancers, including neuroendocrine tumors (NETs). Interestingly, sst5TMD4 has 4 transmembrane domains and its C-terminal tail is consequently exposed towards the extracellular matrix, and could, therefore, be the substrate for proteolytic enzymes.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
Authors: Pedraza-Arévalo S, Del Río-Moreno M, Alors-Pérez E, Castaño J, Luque R,
Keywords: sst5TMD4, derived peptides, malignancy, endocrine-related cancer,
Introduction: Gastric neuroendocrine neoplasms (g-NENs) are a heterogeneous group of tumors.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
Authors: Wei Y, Bai J, He N, Hua X, Tang Q,
Keywords: g-nen, human transcriptome array, differentially expressed genes, extracellular matrix,
#529 Alternative Splicing and Differential Gene Expression in Pancreatic NETs
Introduction: Protein isoforms resulting from differentially spliced mRNA may constitute peculiar drug targets or markers for cancer diagnosis. We here present a new DNA array that allows identification of splice variation and differential expression for 357 G protein-coupled receptors (GPCR) and 11 proteins of the extracellular matrix.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Körner J, Schäfer C, Schulz P, Wiedenmann B, Grötzinger C,
Keywords: pNET,
#357 Alternative Splicing and Differential Gene Expression in Pancreatic NETs
Introduction: Alternative splicing is an important mechanism to increase diversity of the proteome in higher organisms. These protein isoforms can provide as a selective drug target or marker for cancer diagnosis. We present here a new DNA array that allows identification of splice variation and differential expression of 357 G protein-coupled receptors (GPCR) and 11 proteins of the extracellular matrix.
Conference:
Presenting Author:
Authors: Körner J, Wiedenmann B, Grötzinger C,
Keywords: splice variants array,